ISO 17099:2014 addresses the following:
a) confidentiality of personal information for the customer and the laboratory
b) laboratory safety requirements
c) radiation sources, dose rates, and ranges used for establishing the calibration reference dose-effect curves allowing the dose estimation from CBMN assay yields and the minimum resolvable dose
d) performance of blood collection, culturing, harvesting, and sample preparation for CBMN assay scoring
e) scoring criteria
f) conversion of micronucleus frequency in binucleated cells into an estimate of absorbed dose
g) reporting of results
h) quality assurance and quality control
i) informative annexes containing examples of a questionnaire, instructions for customers, a microscope scoring data sheet, a sample report and advice on strengths and limitations of current automated systems for automated micronucleus scoring.